Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Lacinia at quis risus sed vulputate odio ut. Sit amet consectetur adipiscing elit. Gravida dictum fusce ut placerat orci nulla pellentesque. Sit amet consectetur adipiscing elit. Aliquet bibendum enim facilisis gravida neque convallis a cras. Tellus at urna condimentum mattis pellentesque id nibh. Facilisis volutpat est velit egestas dui id ornare arcu odio. Non sodales neque sodales ut etiam sit amet nisl. Cras semper auctor neque vitae tempus quam pellentesque nec nam. Mauris augue neque gravida in fermentum et. Pellentesque dignissim enim sit amet venenatis urna.

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Vel quam elementum pulvinar etiam non. Est pellentesque elit ullamcorper dignissim cras tincidunt lobortis feugiat. Amet commodo nulla facilisi nullam vehicula ipsum. Cras semper auctor neque vitae tempus quam pellentesque. Pretium viverra suspendisse potenti nullam. Quis imperdiet massa tincidunt nunc pulvinar sapien et ligula ullamcorper. Faucibus ornare suspendisse sed nisi. Sed egestas egestas fringilla phasellus faucibus. Luctus accumsan tortor posuere ac ut consequat semper. Malesuada proin libero nunc consequat. Gravida quis blandit turpis cursus. Morbi tempus iaculis urna id volutpat lacus laoreet. Lacus sed turpis tincidunt id aliquet risus feugiat in. Congue mauris rhoncus aenean vel elit scelerisque mauris pellentesque pulvinar. Nisi lacus sed viverra tellus in hac. Congue mauris rhoncus aenean vel elit scelerisque mauris. Velit euismod in pellentesque massa placerat duis ultricies lacus. Mattis nunc sed blandit libero volutpat sed cras.

Vel pharetra vel turpis nunc eget. Hac habitasse platea dictumst quisque sagittis purus sit amet volutpat. Tristique senectus et netus et malesuada fames ac. Facilisis magna etiam tempor orci eu. Nunc vel risus commodo viverra. Metus aliquam eleifend mi in nulla posuere sollicitudin. Mus mauris vitae ultricies leo integer malesuada nunc. Adipiscing elit duis tristique sollicitudin nibh sit amet commodo. Viverra accumsan in nisl nisi. Morbi blandit cursus risus at ultrices mi. Nisl vel pretium lectus quam id leo. Egestas sed tempus urna et. Non curabitur gravida arcu ac tortor dignissim convallis aenean. Bibendum arcu vitae elementum curabitur vitae nunc sed velit. In eu mi bibendum neque egestas. Nisl suscipit adipiscing bibendum est ultricies integer quis auctor. Ultrices dui sapien eget mi proin sed libero enim sed. Nunc scelerisque viverra mauris in aliquam sem. Commodo quis imperdiet massa tincidunt. Pretium fusce id velit ut tortor pretium viverra.

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Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Tempor nec feugiat nisl pretium fusce id velit ut. Purus gravida quis blandit turpis. Scelerisque viverra mauris in aliquam sem fringilla. Metus dictum at tempor commodo ullamcorper a lacus. Aliquam eleifend mi in nulla posuere sollicitudin. Feugiat pretium nibh ipsum consequat. Quis imperdiet massa tincidunt nunc. Porta lorem mollis aliquam ut porttitor leo. Viverra suspendisse potenti nullam ac tortor vitae. Elementum eu facilisis sed odio morbi quis. Pretium nibh ipsum consequat nisl. Ut etiam sit amet nisl purus in mollis nunc. Enim blandit volutpat maecenas volutpat blandit aliquam. Mauris ultrices eros in cursus. Amet aliquam id diam maecenas ultricies.

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The Council for Responsible Nutrition (CRN) revealed in its 2021 Consumer Survey on Dietary Supplements that 80% of Americans are using dietary supplements for natural health care.¹ This statistic speaks volumes in support for the nutraceutical industry, but formulators and manufacturers should never forget how easily sales can come to a crashing halt following a publication releasing data suggesting potential harm from a natural supplement.² A negative report about even a single ingredient can cause a catastrophic decline in revenue and loss of trust with the consumers. This can have a cascading negative impact on other product lines as well, so it becomes a big issue especially for larger established companies with multiple product lines.

However, the exact opposite can occur when structure/functions and safety claims are scientifically supported by clinical studies, such as what’s currently occurring with the coronavirus pandemic and the increased uptake of immune-supporting supplements like vitamins D, C and zinc.^1,3

With a direct correlation between clinical research and sales, along with consumers and companies like Amazon demanding data to show the safety and efficacy of nutraceutical products, you’d assume more formulators and manufacturers would invest time and financial resources to conduct clinical studies on their products. Unfortunately, this testing isn’t occurring nearly enough, especially within the herbal supplement sector.

The Herbal Supplement Industry Needs to Change

A majority of herbal ingredient suppliers do not perform clinical trials on their formulas due to cost and timing constraints. So instead, they only support their structure/function claims on the rationale that herbal extracts have successfully been used for centuries. You can quickly spot these companies when reading about their products, because all you see are blanket statements that the herbs in their formula are “traditionally used for…”. While these traditional use statements may be true, to solely rely on them as the only source for substantiation is irresponsible, as they do not provide any type of safety and efficacy support for the specific product they are selling.

There are also ingredient suppliers and manufacturers who attempt to leverage research conducted by other companies selling similar herbal formulas as support for their own products. This not only discourages innovation and high-quality testing in the industry but is also detrimental to the consumer who purchases this product, because what they end up taking may be a less effective, inferior and potentially unsafe version of what was properly tested.

In order to establish credibility for herbal use in the supplement industry, traditional usage claims must be complemented by rigorous clinical studies on the actual herbal product being formulated and sold. The catalyst for change must begin with formulators. It’s imperative that they choose to only work with ingredient partners who develop and clinically test their herbal ingredients.  

The Importance of Documented Proof and Manufacturing

Another key component to creating premium herbal products is to have the same company who designed and tested the formula play a role in manufacturing them. This puts a safeguard in place to ensure that the final deliverable is safe and efficacious. There are a handful of reputable herbal companies that follow this trifecta approach, and it’s evident in the product documentation they provide with their ingredient formulas to clients.

The following detailed testing and documentation should be standard protocol in the herbal extract sector of what’s provided to finished product manufacturers/brands:

• Safety and efficacy data on the herbal formula that’s been created, including human clinical studies
• HPTLC fingerprinting analysis, which authenticates which specific herb species were used. Some herbs may have more than 100 species and using the wrong species could be dangerous.
• Verification that the herbal extracts used are standardized to the claimed percentage of the active compound since the active compound is what gives the benefit.
• Real-time and accelerated stability testing data to determine the shelf-life of the product.
• Third-party lab reports to check for the content of impurities, such as heavy metals and microbials.
• Third-party certifications such as GMP, ISO 22000, Non-GMO, Kosher, Halal and Vegan.

Transparency and the Future

One company that has become an industry leader and is paving the way for other herbal ingredient suppliers to follow is Karallief. Karallief has always put science first, and they adhere to every one of the strict protocols mentioned in this article.

Karallief’s diverse team of experts consists of MDs, Naturopathic doctors, R&D industry leaders and herbal scientists. The company also holds an exclusive partnership with a world-renowned herbal extract manufacturer and high-end research facility, bringing a combined 23+ years of experience and 25 international patents amongst their combined groups.

Karallief has successfully united the powerful forces of nature, science and innovation, and this is evident in their clinically tested herbal formulas like Easy Climb joint support, KaraLiv liver support and KaraHeart heart support.

To learn more about partnering with Karallief click here.

References:

1. https://www.crnusa.org/newsroom/crn-reveals-initial-data-2021-consumer-survey-dietary-supplements
2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518024
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750357

Figure 1. Solid Waste Industry - Conversion of AEBITDA into Adjusted FCF, 2009-2020E

Ticker	2009	2010	2011	2012	2013	2014	2015	2016	2017	2018	2019E	2020E
ADSW	na	na	na	(29.3%)	22.4%	25.4%	25.5%	22.9%	31.5%	34.1%	32.4%	31.9%
CWST	0.7%	(6.2%)	(0.2%)	(16.6%)	1.4%	(10.3%)	19.1%	22.5%	30.1%	34.1%	34.2%	36.9%
CVA	76.1%	67.3%	56.9%	53.4%	46.4%	50.4%	34.3%	42.0%	32.4%	21.9%	29.5%	32.4%
RSG	29.7%	31.3%	36.3%	33.6%	29.3%	28.5%	31.7%	33.3%	33.7%	41.9%	38.6%	39.2%
WCN	52.6%	47.6%	51.4%	52.2%	45.9%	44.8%	48.3%	51.4%	52.3%	56.1%	54.6%	56.3%
WM	38.0%	36.3%	36.5%	25.1%	38.8%	96.9%	41.0%	44.9%	44.2%	49.4%	46.4%	42.5%
W Average	37.7%	36.7%	38.4%	30.8%	35.7%	62.4%	37.1%	40.5%	41.0%	46.1%	44.0%	42.9%
Average	39.4%	35.3%	36.2%	19.7%	30.7%	39.3%	33.3%	36.2%	37.3%	39.6%	39.3%	39.9%